Isoprinosine™ is a drug with immunomodulatory and antiviral properties. It exerted beneficial clinical effect in patients with HSV, HZV, HPV, HBV, influenza and subacute sclerosing panencephalitis. We established an elevation of PBMC and absolute number of small and large lymphocytes in adult participants prior and …

After achieving a durable on-treatment virological response with NUC (nucleos(t)ide analogues), adding an immunomodulating agent seems to have beneficial effect on the course of chronic HBV disease. Methods: Nine patients were investigated (5 – HBeAg(-) and 4 – HBeAg(+). All patients achieved durable on-treatment virological …

The purpose of the study was to evaluate, by examination of periapical radiographs, whether the application of intra-radicular posts in endodontically treated teeth can lead to the development of periapical lesions. A total of 103 panoramic radiographs from 103 patients (263 endodontically treated teeth) from …

The aim of this study was to test the effect of combined usage of ceftiofur with beta-cloprostenol and busereline for puerperal endometritis treatment in dairy heifers. The results received suggest that combined usage of ceftiofur with cloprostenol and buserelin successfully treats puerperal endometritis and significantly …

Anemia of diverse etiology occurs in about 75% of patients with liver cirrhosis. Mucosal injury due to portal hypertension is an underestimated cause of occult bleeding and iron-deficiency anemia. Iron isomaltoside is a parenteral agent with low free-iron toxicity that is used as a short-term …

Wilson’s disease is an autosomal recessive disorder. It results in the accumulation of copper in the liver, brain, and other organs. An impairment in the biliary excretion process leads to copper accumulation in the liver, which progressively damages the liver, leading to cirrhosis. Wilson’s disease …

Sarcoidosis is a chronic multisystem disease, characterized by the presence of noncaseating epithelioid granulomas. The commonest site of affection are the lungs and the the intrathoracic lymph nodes, seen in 90 % of the patients (1). Involvement of intraabdominal viscera is less frequent, it may …

Human papillomaviruses constitute the most widely spread sexually transmitted viral infection world-wide. In about 1% of the cases, a continuing HPV infection can lead to the appearance of precancerous conditions. In a subsequent carcinoma progression, different types of cancer can develop – cervical, rectal, penile, …

The present article introduces a new technique for chairside provisional fixed partial dentures fabrication. The described direct technique is suitable for a fast and relatively easy fabrication of provisional single crowns or small bridges. It does not necessitate any preliminary laboratory stages (such as wax-up …