Abstract:

There has been a reported number of cases showing a wide variety of oral alterations with the potential of being associated with COVID-19. We present a case report of a 59-year-old female. The diagnosis for SARS-CoV-2 was confirmed by a positive antigen test. The patient noticed an aphthous-like lesion on the right side of the lower lip that presented from the first day of the disease. The patient suffered also from headaches that became stronger; she had a sore throat, pain in both ears, dysgeusia, and anosmia. On the seventh day the patient felt stomach ache and nausea, with the lesion being most painful compared to the previous days. After the tenth day the aphthous-like lesion was not visible, but still painful. Two months later the lesion was no longer visible, but the  patient still felt a concavity in the area when exploring it with her tongue. No pain or discomfort was described at this stage.

A variety of oral lesions in SARS-CoV-2 disease have been reported in the literature. Regarding oral changes, usual clinical appearance described comprises aphthous-like lesions. Older age and severity of COVID-19 are the most common factors that predict severity of oral lesions.

The exact aetiology and pathogenesis of oral changes in patients with this viral infection are not yet well known. More studies are required to elaborate and confirm the relationship between COVID-19 and the described oral manifestations of SARS-CoV-2.