MedInform

Journal of Medical and Dental Practice

www.medinform.bgISSN 2367-6795

Issue One 2024

2024, Vol. 11, issue 1, (January)

Publisher: Medinform LTD
ISSN: 2367-6795
Pages: 1753-1840
Date of close: 2024/06/10

Literature Review

Saliva as potential diagnostic tool – composition, advantages, diagnostic methods and significance in diseases

Abstract:

The advantages of saliva as a potential diagnostic fluid and the abundant salivary composition provide opportunities for easy and accessible examination of salivary content changes in a number of oral and general diseases. The analytical methods of mass spectrometry, matrix assisted laser desorption/ionization, enzyme linked immunoassay and immunofluorescence enable the identification of a large number of biomolecules. Alterations in the expression of signaling and immunoreactive molecules in cases of oral potentially malignant disorders and oral squamous cell carcinoma, where some cytokines show potential to be useful as diagnostic and prognostic factors, are of particular interest.

 

Keywords: saliva, cytokines, diagnostic significance

Authors:

Angel Adamov; Department of Dental, Oral and Maxillofacial Surgery, Faculty of Dental Medicine, Medical university-Sofia; Email this author
Konstantin Stamatov; Department of Dental, Oral and Maxillofacial Surgery, Faculty of Dental Medicine, Medical university-Sofia;

Corresponding Author:

Angel Adamov; Department of Dental, Oral and Maxillofacial Surgery, Faculty of Dental Medicine, Medical university-Sofia; Email this author