Abstract:

Subject: Psoriasis is a chronic, skin disorder with a genetic predisposition. Oral manifestation of psoriasis is a rare and controversial finding. Lesions are always a diagnostic dilemma.
Methodology: A clinical case of a 71-year-old male patient diagnosed with psoriasis is presented. He complained of a lesion on the tongue – a small area of ulceration, noticed about 2 years ago.
Results: Clinical examination revealed a lesion on the dorsum of the tongue, in its anterior aspect, with a centrally depressed area and leukoplakic changes at the periphery. The changes are non-typical and on this occasion the patient was recommended to undergo a biopsy for diagnostic purpose. Histopathological examination showed stratified squamous epithelium with a dense inflammatory infiltrate, acanthosis, areas with suprabasal detachment formation, as well as intraepithelial microabscesses with acantholysis.
Conclusion: The analysis of the clinical features and histopathological data in the presented case are consistent with psoriasis of the oral mucosa. It is a rare disease that is difficult to differentiate from other dermatoses with manifestations in the oral cavity. Therefore, it should be considered in the differential diagnosis of oral lesions.

Keywords: psoriasis, psoriasis of the tongue, oral lesions, oral mucosa