Isoprinosine is a drug with immunomodulatory and antiviral properties. It increases IFN- gamma, IL-2, IL-10, and TNF-alpha serum levels at 7th to 10th day in healthy volunteers. In the present study serum levels of IL-2; IL-4; IL-6; IL-10, TNF-alpha, IFN- gamma, and IP-10 were evaluated …

Hemolytic uremic syndrome is a form of thrombotic microangiopathy which takes its clinical course by a triad of symptoms: microangiopathic hemolytic anemia, thrombocytopenia and acute renal failure. We review a considerable amount of literature about the mentioned problem. Two kinds of hemolytic uremic syndrome are …

An overview of the literature on the role of periodontopathogenic microorganisms and chronic periodontitis in the emergence and development of rheumatoid arthritis is presented. The paper discusses the microbiological and genetic factors, environmental factors and the pathogenesis of the two diseases and presents evidence for …

Oral cancer is currently the sixth most common carcinoma worldwide and  squamous-cell carcinoma accounts for more than 90 % of all cases. The earliest diagnosis of squamous-cell carcinoma, the better the outcome of the treatment and the prognosis. The choice of treatment depends on tumour …

Mandibular diastema does not occur often, however, its abnormal characteristics have more disturbing implications. A major etiologic factor for mandibular diastema are pernicious habits associated with tongue thrust in a low rest position. The aim of this study is to report the approach and effects …

Apical surgery is considered a standard oral surgical procedure. It is often a last resort to surgically maintain a tooth with a periapical lesion that cannot be managed with conventional endodontic (re-)treatment. The main goal of apical surgery is to prevent bacterial leakage from the …

Dental wear under its different forms, such as abrasion and especially erosion, becomes more and more frequent in various populations around the globe. Recent studies indicate that the problem spreads on an epidemic scale and according to some researches the overall prevalence is estimated to …

We present a 56-years-old patient with a clinical and biochemical picture of acute hepatitis, but for the fourth time in her life after an eighteen- years period with normal liver tests. The patient had also had concomitant increase in alpha- fetal protein (AFP). After exclusion …

The impaired balance in articulation and occlusion can be due to anatomical or iatrogenic causes, nevertheless, it always violates the coordination of morphological structures of the masticatory apparatus and their function. The authors of the present paper aim to explore all available literature in an …