Journal of Medical and Dental Practice

www.medinform.bgISSN 2367-6795

Issue Two 2016

2016, Vol. 3, issue 2, (December)

Publisher: Medinform LTD
ISSN: 2367-6795
Pages: 422-513
Date of close: 2016/12/09

Literature Review

Salivary biomarkers in patients with end-stage chronic kidney disease


Chronic kidney disease is defined as a progressive and irreversible deterioration of the renal function, with a rising incidence rate on a global scale. A wide range of oral changes can be observed in patients with end-stage renal disease, ones that reflect the changes occurring in harder and softer oral tissues, often as a result of the general manifestations of the basic condition. The objective of this review is to discuss the changes in the biological contents of the oral cavity with an emphasis on the most commonly used biological parameters consistent with the characteristics of chronic kidney diseases.


Anna Nenova-Nogalcheva; Departament of Oral Surgery, Faculty of Dental medicine, Medical University - Varna;
Assya Krasteva; Department of oral and imaging diagnostics, Faculty of Dental medicine, Medical University;
Kamen Nogalchev; Department of Prosthetic Dentistry, Faculty of Dental medicine, Medical University – Varna;

Corresponding Author:

Anna Nenova-Nogalcheva; Faculty of Dental medicine, Medical University - Varna; Email this author