MedInform

Journal of Medical and Dental Practice

www.medinform.bgISSN 2367-6795

Issue One 2026

2026, Vol. 13, issue 1

Publisher: Medinform LTD
ISSN: 2367-6795
Pages: 2307-2414
Date of close: 2026/01/01

Case Reports

Management of MIH-Affected Tooth Using a CAD/CAM Hybrid Composite Inlay: A Case Report

Molar–incisor hypomineralization (MIH) is a developmental enamel defect affecting at least one first permanent molar and often the incisors, presenting as asymmetrical, well-demarcated opacities ranging from mild discoloration to extensive post-eruptive breakdown. Affected teeth show reduced mineralization, increased sensitivity, and higher susceptibility to caries, fractures, …

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Authors:

Nedana Georgieva; Private Dental Practice;

Original Article

Long-Term in Vitro Expansion of Stem Cells from the Apical Papilla: Proliferation Capacity and Phenotypic Stability

Stem cells from the apical papilla (SCAP) represent a valuable dental mesenchymal stem cell population with high proliferative and regenerative potential. The present study investigated the effects of long-term in vitro expansion on the proliferative behavior, senescence progression, phenotypic stability, and viability of SCAP. Cells …

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Authors:

Zornitsa Mihaylova; Research institute of innovative medical science, Medical University Sofia, Bulgaria; Department of Dental, Oral and Maxillofacial surgery, Faculty of Dental Medicine, Medical University Sofia; Email this author
Nikolay Ishkitiev; Department of Chemistry and Biochemistry, Medical Faculty, Medical University Sofia, Bulgaria;
Evgeniy Aleksiev; Department of Dental, Oral and Maxillofacial surgery, Faculty of Dental Medicine, Medical University Sofia;
Marina Miteva; Department of Chemistry and Biochemistry, Medical Faculty, Medical University Sofia, Bulgaria;;

Case Reports

Conservative Direct Restorations for Traumatic Anterior Teeth Using Injection Molding Technique: A Case Report

Dental trauma is a common clinical condition with significant functional, aesthetic, and psychosocial consequences, particularly in children and adolescents. Anterior teeth are most frequently affected, and timely, appropriate management is essential to ensure a favorable prognosis and to minimize pulpal and periodontal complications. This article …

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Authors:

Nedana Georgieva ; Private Dental Practice ; Email this author

Case Reports

Combined Fluoride Varnish and CPP-ACP Therapy for MIH-Related Hypersensitivity: A Clinical Case

Molar–incisor hypomineralization (MIH) is a qualitative, systemically induced enamel defect affecting one or more first permanent molars and often the permanent incisors, frequently associated with demarcated opacities, post-eruptive enamel breakdown and marked hypersensitivity, which complicate oral hygiene and dental treatment and negatively affect quality of …

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Authors:

Zdravka Yaneva; Department of Pediatric Dental Medicine, Faculty of Dental Medicine, Medical University – Sofia;
Nikolay Apostolov; Department of Prosthetic Dental Medicine, Faculty of Dental Medicine, Medical University – Sofia;

Literature Review

Forensic dentistry as an interdisciplinary scientific field

Forensic dentistry, or forensic odontology, is an interdisciplinary scientific field that applies dental knowledge to legal and judicial investigations. It plays a crucial role in identifying human remains, analysing dental and maxillofacial trauma, examining bite marks, and constructing biological profiles in criminal, civil, and mass-disaster …

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Authors:

Vladimir Panov; Department of Conservative Dentistry and Oral Pathology, Faculty of dental medicine, Medical University -Varna;

D-PTFE Membranes for Ridge Preservation: a Randomized Controlled Trial

Background: Alveolar ridge preservation (ARP) is a method used to reduce the external resorption of the ridge and increase bone deposition in the post-extraction site. Recently, dense polytetrafluoroethylene (d-PTFE) membranes have been adopted for ARP. This research investigates the application of d-PTFE membranes for ARP. …

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Authors:

Ralitsa Yotsova ; Department of Oral Surgery, Faculty of Dental Medicine, Medical University of Varna, Bulgaria;

Original Article

In Vivo Changes in Open Circuit Corrosion Potentials After Fixed Orthodontic Appliance Placement: Prospective Clinical Study

Fixed orthodontic appliances introduce metallic elements into the oral cavity and may affect the local electrochemical environment during treatment. Continuous exposure to saliva, dental biofilm, dietary factors, and changes in oral acidity may influence the corrosion behavior of orthodontic materials under clinical conditions. The aim …

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Authors:

Stefani Doshkova; Department of Imaging Diagnostics, Dental Allergology and Physiotherapy, Faculty of Dental Medicine, Medical University of Plovdiv, Bulgaria; Email this author
Iliyana Stoeva; Department of Imaging Diagnostics, Dental Allergology and Physiotherapy, Faculty of Dental Medicine, Medical University of Plovdiv, Bulgaria;

Literature Review

Biological Effects of Materials Used in Orthodontic Treatment

Orthodontic treatment involves prolonged contact between dental materials and the oral environment, which creates conditions for continuous biological exposure throughout therapy. Orthodontic appliances remain in situ for months or years and are subjected to mechanical stress, thermal fluctuations, changes in oral acidity and microbial activity. …

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Authors:

Stefani Doshkova; Department of Imaging Diagnostics, Dental Allergology and Physiotherapy, Faculty of Dental Medicine, Medical University of Plovdiv, Bulgaria; Email this author
Iliyana Stoeva; Department of Imaging Diagnostics, Dental Allergology and Physiotherapy, Faculty of Dental Medicine, Medical University of Plovdiv, Bulgaria;

Original Article

Impact of different cleaning methods on the flexural strength of “ThermoSens” denture base materials

A variety of thermoplastic materials, including “ThermoSens”, a nylon-based denture base material, can be used in the fabrication of removable partial dentures. Assessing the mechanical properties of these materials is crucial, as they directly impact the function and longevity of the dentures. Thermoplastic polyamides, known …

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Authors:

Rumen Radev; Department of Prosthetic Dental Medicine, Faculty of Dental Medicine, Medical University – Sofia, Bulgaria. ;
Zdravka Yaneva; Department of Paediatric Dental Medicine, Faculty of Dental Medicine, Medical University – Sofia, Bulgaria;
Nikolay Apostolov; Department of Prosthetic Dental Medicine, Faculty of Dental Medicine, Medical University – Sofia, Bulgaria. ;

Original Article

Evaluating the maximum bite force in edentulous and non-edentulous patients using a gnathodynamometer

In clinical dentistry, evaluating the maximum bite force (MBF) provides insights into the functional capabilities of patients, particularly when comparing those with natural dentition to those experiencing tooth loss. Natural dentition typically exhibits superior MBF due to optimal proprioceptive feedback and periodontal ligament support. This …

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Authors:

Rumen Radev; Department of Prosthetic Dental Medicine, Faculty of Dental Medicine, Medical University – Sofia, Bulgaria. ;
Nikolay Apostolov; Department of Prosthetic Dental Medicine, Faculty of Dental Medicine, Medical University – Sofia, Bulgaria. ;
Zdravka Yaneva; Department of Paediatric Dental Medicine, Faculty of Dental Medicine, Medical University – Sofia, Bulgaria;
Dimitar Kirov; Department of Prosthetic Dental Medicine, Faculty of Dental Medicine, Medical University – Sofia, Bulgaria. ;

Case Reports

Management of a Maxillary Second Molar with Two Palatal Canals: A Case Report

Anatomical variations in root canal systems present significant challenges in endodontic treatment and may compromise outcomes if not properly identified and managed. Maxillary second molars typically present with three canals; however, the presence of two palatal canals is a rare variation that may be easily …

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Authors:

Dimitar Kosturkov; Department of conservative dentistry, Faculty of Dental Medicine, Medical University, Sofia, Bulgaria; Research Institute of Innovative Medical Science, Medical University Sofia, Bulgaria;

Case Reports

Single-Visit Endodontic Treatment of a Mandibular Second Molar with S-Shaped Mesial Root Canal Curvature: A Case Report

Root canal treatment of teeth with complex canal morphology, such as S-shaped curvatures, presents significant clinical challenges and increases the risk of procedural errors. Mandibular second molars may exhibit severe canal curvatures, particularly in the mesial root, complicating instrumentation and disinfection. This case report describes …

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Authors:

Dimitar Kosturkov; Department of conservative dentistry, Faculty of Dental Medicine, Medical University, Sofia, Bulgaria; Research Institute of Innovative Medical Science, Medical University Sofia, Bulgaria; Email this author