Oxidative stress (OS) is defined as imbalance between the accumulation and elimination of free radicals in tissues, in which accumulation prevails. Maintaining homeostatic levels of OS is function of the antioxidant defence (AOD), which is based on catalytic, coordination and irreversible chemical interactions with RS. …

Introduction   Hepatocellular carcinoma (HCC) represents more than 90% of primary liver cancers and is a major global health problem. In the era of Direct acting agents (DAA) for treatment of hepatitis C virus (HCV), sustained virological response (SVR) is achieved in more than 80% …

We report the case of a 23-year-old female dental medicine student with contact dermatitis on her hands caused by methacrylates. Forty-eight-hour closed patch testing showed positive reactions to Ethylenglicol dimethacrylate, 1,6 – Hexanediol diacrylate, 1,4 – Butanediol dimethacrylate, Drometrizole . These are identified as contact …

Introduction: Educators should be involved in children oral health education due to the fact that the children spend a significant amount of time with them in the kindergarten, where they could be taught good health habits. They could emphasize and consolidate knowledge about the significance …

Lamivudine (LAM) is not recommended in the treatment of chronic hepatitis B due to high-rate of resistance: 49% to 70% after 3rd and 5th treatment year. LAM-resistance is more frequent in cases with high viral load or lack of complete HBV-DNA suppression within 6 months. …

The aim of the study was to evaluate the morphological changes in the liver biopsies from patients with chronic hepatitis C (CHC) and heroin abuse (HA). Material and methods: In the study were included 10 patients with CHC and HA (9 m, 1 f, mean …

Osteoarthritis is a degenerative joint disease, affecting approximately 27 million Americans. It can affect any joint, but it occurs most often in knees, hips, lower back and neck, small joints of the fingers and the bases of the thumb and big toe.   We present …

We present data from a single hepatology centre in Bulgaria which started its activity in the late 1990s. Currently 427 patients are treated with nucleotide or nucleoside analogues (NUCs), 104 of whom with liver cirrhosis. The majority – 60% of the patients – are diagnosed …

Pharmacological behavior management is necessary for young children with extensive caries (ECC), children with special health care needs and non-cooperative children.   The aim of this study is to assess the different types of materials used for the dental treatment of children under general anesthesia …

The children treated under general anesthesia are mainly 3 groups: children with early childhood caries (ECC); anxious children and children with special health needs. The study aimed at establishing the oral hygiene level in a group of children treated under general anesthesia. Subject of monitoring …

Epstein-Barr virus and Cytomegalovirus have different oral manifestations which could be presented in the oral cavity most commonly as non-specific oral ulcerations and lymphadenopathy. A lot of people acquire primary infection with Cytomegalovirus and if they later become immunosuppressed, such as human immunodeficiency virus (HIV), …